FLIRT: fast local infrared thermogenetics for subcellular control of protein function
Temperature-sensitive (ts) mutant proteins are great tools to analyze cell-regulative processes by temporally affected protein interactions. However, many observations are based on experiments where temperature shifts in the whole sample (e.g. embryos), and thus are missing spatial regulative aspects. In the study of S.M. Hirsch et al. (nature methods, 2018) they present FLIRT, which stands […]