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NWG Göttingen 2019
13th meeting of the German Neuroscience Society

Mar 20-23, 2019, Göttingen, Germany
Booth No. 8

 

SFN - Neuroscience 2019
50th annual meeting of the Society for Neuroscience

Oct 19-23, 2019, Chicago, IL, USA
Booth No. 1468

 

BPS San Diego 2020
64th annual meeting of the Biophysical Society

Feb 15-19, 2020 San Diego, CA, USA
Booth No. 710

ChR Photoactivation

Light stimulation in acute brain slices of Channelrhodopsin-2 transfected mice

Light stimulation in acute brain slices of Channelrhodopsin-2 transfected mice was used to map excitatory inputs from the CA3 area into the CA1 area of the hippocampus.

 

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Photoactivation of neurons in distinct areas of the spinal chord

Neuronal activity related to locomotion was analysed in isolated spinal chords from transgenic mice possessing photoactivatable channels based on Channelrhodopsin-2 (ChR2).

 

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Light-induced action potentials, photocurrent and light-induced IPSCs

Whole cell recording from the superficial spinal dorsal horn of VGAT::ChR2 BAC transgenic mice. (A) DIC microscopy image of a patched cell. Laser beam (473nm, spot diameter 10 µm) is represented by the blue spot on the somata. (B) Current-clamp mode recording showing light-induced firing in response to patterned blue laser stimulation at 10Hz (0.8μW/μm2, 5ms pulse width). (C) Photocurrent induced by 1s light exposure in voltage-clamp.

 

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