Open-Source Inverted Microscope Platform
The openFrame is a compact, modular, extensible, open-source microscope platform conceived by the Photonics Group at Imperial College London and co-developed by Cairn Research.
The modular microscope is available at a component level or as custom configured integrated system. Being an open-source project, the fundamental building blocks can be machined in your own workshop based on the STEP files provided on the openScopes.com website.
The compact and stable platform is designed from the ground up to work with a wide range of current and legacy components and is typically controlled via MicroManager or other open-source software. This versatile platform is literally centered around the chosen objective lens, enabling a high degree of optimization and making it an excellent base for rapid instrument prototyping or application development.
- Wide-field fluorescence
- Brightfield / Darkfield / Phase contrast
- Photomanipulation like FRAP, Optogenetic, Photoconversion, Ablation, etc.
- Simultaneous/ratiometric calcium and voltage imaging
- Confocal imaging
- High content imaging
- Total Internal Reflection Fluorescence (TIRF)
- Fluorescence Lifetime Imaging (FLIM)
- Single Plane Illumination Microscopy (SPIM)
- Single molecule and super resolution STORM/PALM/SIM
- Containment labs (compact and easy to sterilize)
- Polarization studies (anisotropy)