Entries by

Investigating DNA Repair Pathways by Local UV-C Irradiation

DNA damage was induced in cultured living cells by localized 266 nm radiation (sub-nuclear damage induction). GFP tagged repair factor XPA (GFP-XPA) was used as general reporter for an induced DNA damage. Co-localization analysis with specific Markers (TUNEL & CPD) revealed, that different power levels of pulsed UV-C irradiation can induce different kind of DNA […]